Chondroitin sulfate is a natural substance found in the connective tissues of animals, particularly in cartilage. It is often used as a dietary supplement to support joint health and may help reduce pain and improve mobility in individuals with conditions like osteoarthritis. This compound is commonly combined with glucosamine in supplements, as both are believed to contribute to the maintenance and repair of cartilage. While some studies suggest benefits, the effectiveness of chondroitin sulfate can vary among individuals, and more research is needed to fully understand its impact on joint health.