Cholestyramine is a medication primarily used to lower high levels of cholesterol in the blood. It works by binding to bile acids in the intestines, preventing their reabsorption. This process prompts the liver to use more cholesterol to produce new bile acids, thereby reducing overall cholesterol levels. In addition to its cholesterol-lowering effects, cholestyramine can also help manage certain conditions like pruritus associated with liver disease. It is typically taken as a powder mixed with water or other liquids. Common side effects may include gastrointestinal issues, such as constipation or bloating.