cerebral ALD
Cerebral ALD, or cerebral adrenoleukodystrophy, is a rare genetic disorder that primarily affects the brain and adrenal glands. It is caused by mutations in the ABCD1 gene, which leads to the accumulation of very long-chain fatty acids in the body. This buildup damages the myelin sheath, the protective covering of nerve cells, resulting in neurological symptoms.
Symptoms of cerebral ALD can include behavioral changes, cognitive decline, and motor difficulties. The condition typically manifests in childhood, often between ages 4 and 8, and can progress rapidly. Early diagnosis and intervention are crucial for managing the disease and improving outcomes for affected individuals.