Calamine is a pinkish powder made from a mixture of zinc oxide and iron oxide. It is commonly used in topical ointments and lotions to soothe skin irritations, such as rashes, insect bites, and chickenpox. Calamine works by providing a cooling effect and helping to dry out oozing skin. In addition to its soothing properties, calamine is often found in over-the-counter products like calamine lotion. This lotion is easy to apply and is known for its ability to relieve itching and discomfort. It is a popular choice for treating minor skin issues due to its gentle and effective nature.