Beta-2 receptors are a type of protein found on the surface of certain cells in the body. They belong to a group called adrenergic receptors, which respond to hormones like epinephrine (adrenaline). When activated, beta-2 receptors play a crucial role in relaxing smooth muscles, particularly in the airways, making them important for respiratory function. These receptors are primarily located in the lungs, blood vessels, and uterus. Activation of beta-2 receptors can lead to bronchodilation, which helps improve airflow in conditions like asthma. Medications known as beta-2 agonists are often used to stimulate these receptors and provide relief from respiratory issues.