Arginase II is an enzyme that plays a crucial role in the urea cycle, which helps remove excess nitrogen from the body. It specifically catalyzes the conversion of arginine into ornithine and urea, facilitating the elimination of ammonia, a toxic byproduct of protein metabolism. This enzyme is primarily found in the mitochondria of various tissues, including the liver and kidneys. Arginase II is also involved in regulating nitric oxide production, which is important for various physiological processes, including blood flow and immune response. Its activity can influence conditions such as hypertension and inflammation.