Androgen Insensitivity Syndrome (AIS) is a genetic condition that affects sexual development in individuals with XY chromosomes. People with AIS are genetically male but may develop female physical traits because their bodies cannot respond to androgens, which are male hormones. This can result in a range of physical characteristics, from typical female genitalia to ambiguous genitalia. AIS can be classified into complete and partial forms. In complete AIS, individuals have a female appearance and are often raised as girls, while in partial AIS, some male characteristics may be present. Diagnosis typically occurs during puberty or through genetic testing, and management may involve hormone therapy and psychological support.