amyloid precursor protein (APP)
Amyloid precursor protein (APP) is a protein found in the cell membranes of neurons and other tissues. It plays a crucial role in cell signaling and is involved in the growth and repair of neurons. APP can be processed in different ways, leading to the production of various fragments, some of which are important for normal brain function.
One of the most significant concerns related to APP is its connection to Alzheimer's disease. When APP is improperly processed, it can lead to the accumulation of beta-amyloid plaques in the brain, which are characteristic of this neurodegenerative disorder. Understanding APP's function and processing is essential for developing potential treatments for Alzheimer's disease.