Amoeboid movement is a type of locomotion used by certain cells, such as amoebas. This movement occurs when the cell's cytoplasm flows in one direction, forming temporary extensions called pseudopodia. These extensions help the cell to crawl along surfaces by anchoring to the substrate and pulling the rest of the cell forward. This process is driven by the rearrangement of the cell's internal structures, particularly the cytoskeleton. Amoeboid movement is not only essential for the mobility of single-celled organisms but also plays a role in the immune response of white blood cells, allowing them to move toward infection sites.