Alpha agonists are a class of medications that stimulate alpha-adrenergic receptors in the body. These receptors are part of the nervous system and play a role in regulating various physiological functions, including blood pressure and heart rate. By activating these receptors, alpha agonists can cause blood vessels to constrict, leading to increased blood pressure. Commonly used alpha agonists include clonidine and methyldopa, which are often prescribed to treat hypertension (high blood pressure). They can also be used in other conditions, such as attention deficit hyperactivity disorder (ADHD) and certain types of pain management.