Zinc homeostasis refers to the regulation of zinc levels in the body to maintain optimal health. Zinc is an essential trace element that plays a crucial role in various biological processes, including immune function, protein synthesis, and DNA synthesis. The body must balance zinc intake from food and supplements with its absorption, distribution, and excretion to prevent deficiency or toxicity. The body regulates zinc levels through several mechanisms, including the action of zinc transporters, which control zinc absorption in the intestines and its release from cells. Additionally, the liver plays a key role in storing and distributing zinc, while the kidneys help excrete excess amounts. Proper zinc homeostasis is vital for overall health and well-being.