The Yukon-Tanana Uplands is a mountainous region located in central Alaska, primarily within the boundaries of the Yukon-Koyukuk Census Area. This area is characterized by rugged terrain, including hills, valleys, and numerous rivers. The uplands are part of the larger Alaska Interior and are known for their diverse ecosystems, which support various wildlife species. The region is rich in natural resources, including minerals and timber, making it significant for both ecological and economic purposes. The Yukon River, one of the longest rivers in North America, flows nearby, providing vital water resources and transportation routes for local communities.