The USS Preble (DD-880) was a Gearing-class destroyer of the United States Navy, launched on December 1, 1945. It was named after Commodore Edward Preble, a naval officer known for his role in the First Barbary War. The ship was commissioned on April 28, 1950, and served primarily in the Pacific Fleet. Throughout its service, the USS Preble participated in various operations, including the Korean War and the Vietnam War. The destroyer was equipped with advanced weaponry for its time, including torpedoes and anti-aircraft systems. It was decommissioned on December 1, 1983, after over three decades of service.