U.S. Route 222 is a north-south highway located in the eastern United States. It runs approximately 70 miles, connecting the cities of Allentown, Pennsylvania and Lancaster, Pennsylvania. The route primarily serves as a regional connector, facilitating travel between various towns and communities in the area. The highway passes through several counties, including Lehigh and Berks, and features a mix of urban and rural landscapes. Along its path, travelers can find various amenities, including restaurants and gas stations, making it a convenient route for both local commuters and long-distance travelers.