Toxicant-Induced Loss of Tolerance (TILT) refers to a condition where exposure to certain chemicals or toxins leads to a heightened sensitivity to various substances. This can occur after an individual is exposed to specific toxicants, resulting in an inability to tolerate everyday chemicals, foods, or environmental factors that were previously well-tolerated. Individuals experiencing TILT may develop symptoms such as headaches, fatigue, or respiratory issues when exposed to common irritants like perfumes, cleaning products, or pesticides. Understanding TILT is important for identifying and managing sensitivities that can significantly impact a person's quality of life.