Thioamides
Thioamides are a class of organic compounds that contain a sulfur atom bonded to a nitrogen atom, typically in the form of a thiourea structure. They are primarily used in the treatment of hyperthyroidism, a condition where the thyroid gland produces excessive hormones. Thioamides work by inhibiting the enzyme thyroid peroxidase, which is essential for the synthesis of thyroid hormones.
Common examples of thioamides include methimazole and propylthiouracil. These medications help to reduce the levels of thyroid hormones in the body, alleviating symptoms associated with hyperthyroidism. While effective, thioamides can have side effects, such as allergic reactions or liver issues, requiring careful monitoring during treatment.