"The Last Angry Man" is a short story by E.B. White that explores the life of a once-idealistic doctor named Dr. Samuel W. H. Hargrove. As he ages, he becomes increasingly frustrated with the changes in society and the decline of moral values. His anger is directed at the apathy he perceives in the world around him, particularly in the medical profession and the treatment of patients. The narrative highlights the conflict between Hargrove's dedication to his patients and the modern world's focus on profit and efficiency. Through his struggles, the story examines themes of integrity, compassion, and the challenges of maintaining one's principles in a rapidly changing environment.