Systemic inflammation is a widespread immune response that occurs throughout the body, often triggered by infections, injuries, or chronic diseases. Unlike localized inflammation, which affects a specific area, systemic inflammation can impact multiple organs and systems, leading to various health issues. It is characterized by the release of inflammatory markers into the bloodstream, which can be detected through blood tests. Chronic systemic inflammation is linked to several health conditions, including heart disease, diabetes, and autoimmune disorders. Factors such as poor diet, lack of exercise, and stress can contribute to this ongoing inflammation. Managing these factors is essential for reducing systemic inflammation and improving overall health.