Sulfonylureas are a class of medications used to treat type 2 diabetes. They work by stimulating the pancreas to release more insulin, which helps lower blood sugar levels. These drugs are typically taken orally and are often prescribed when diet and exercise alone are not enough to control blood sugar. Common examples of sulfonylureas include glipizide, glyburide, and glimepiride. While effective, they can cause side effects such as low blood sugar (hypoglycemia) and weight gain. Patients using sulfonylureas should monitor their blood sugar levels regularly and consult their healthcare provider for proper management.