St. Joseph, Missouri, is a city located in the northwestern part of the state, along the banks of the Missouri River. Founded in 1843, it played a significant role in westward expansion during the 19th century, serving as a starting point for the Oregon Trail and the California Trail. The city is known for its rich history and cultural heritage, including the Pony Express, which began operations here in 1860. Today, St. Joseph features various museums, parks, and historic sites, making it a destination for those interested in American history and outdoor activities.