Spinal Muscular Atrophy Type 4
Spinal Muscular Atrophy Type 4 (SMA Type 4) is a rare genetic disorder that primarily affects adults. It is characterized by progressive muscle weakness and atrophy due to the loss of motor neurons in the spinal cord. Symptoms typically begin in late adolescence or early adulthood and may include difficulty walking, muscle cramps, and reduced muscle tone.
The condition is caused by mutations in the SMN1 gene, which is essential for the survival of motor neurons. While SMA Type 4 is less severe than other forms of spinal muscular atrophy, it can still significantly impact mobility and quality of life. Treatment options focus on managing symptoms and improving function.