Southern Tick-Associated Rash Illness (STARI) is a condition that can occur after a bite from the Lone Star tick. It is characterized by a circular rash that resembles the rash seen in Lyme disease, but STARI is not caused by the same bacteria. Symptoms may also include fatigue, headache, and muscle pain, typically appearing within a week of the tick bite. While STARI is generally considered less severe than Lyme disease, it is important to seek medical attention if symptoms arise. Treatment usually involves antibiotics, and most people recover fully. Preventive measures include avoiding tick-infested areas and using insect repellent.