Somatomedin refers to a group of proteins that are produced in the liver and other tissues in response to growth hormone (GH) stimulation. The most well-known somatomedin is insulin-like growth factor 1 (IGF-1), which plays a crucial role in growth and development, particularly during childhood and adolescence. Somatomedins help promote cell growth and division, influencing various biological processes such as metabolism and tissue repair. They act by binding to specific receptors on cells, triggering a cascade of effects that support overall health and development.