Short-Term Potentiation (STP) is a temporary increase in the strength of synaptic transmission between neurons. This phenomenon occurs when two or more action potentials arrive at a synapse in quick succession, leading to a heightened response in the postsynaptic neuron. STP is crucial for processes like learning and memory, as it enhances communication between neurons. The duration of STP typically lasts from a few seconds to several minutes. It is believed to involve changes in neurotransmitter release and receptor sensitivity, allowing for more effective signaling. Understanding STP helps researchers explore the mechanisms underlying neuroplasticity and cognitive functions.