Short Tandem Repeats (STRs) are sequences of DNA where a short motif, typically 2 to 6 base pairs long, is repeated multiple times in a row. These repeats are found in various locations throughout the genome and can vary in length between individuals, making them useful for genetic profiling and forensic analysis. STRs are commonly used in DNA profiling because their variability helps distinguish between different individuals. In forensic science, analyzing specific STR loci can provide crucial evidence in criminal investigations, while in paternity testing, they help determine biological relationships by comparing the STR patterns of potential relatives.