Separation of Variables is a mathematical technique used to solve ordinary differential equations. The method involves rearranging the equation so that each variable appears on a different side. This allows for the integration of each variable independently, simplifying the problem. Once the variables are separated, you can integrate both sides of the equation. After integration, you typically solve for one variable in terms of the other, leading to a general solution. This method is particularly useful in solving problems in physics, engineering, and other fields where differential equations are common.