Selective Estrogen Receptor Modulators, or SERMs, are a class of drugs that interact with estrogen receptors in the body. They can either mimic or block the effects of estrogen, depending on the specific tissue. This unique ability makes SERMs useful in treating conditions like breast cancer and osteoporosis. SERMs are designed to target specific tissues, providing benefits while minimizing side effects. For example, they can help maintain bone density in postmenopausal women while reducing the risk of estrogen-related cancers. Common examples of SERMs include tamoxifen and raloxifene.