Selective Estrogen Receptor Modulators, or SERMs, are a class of drugs that interact with estrogen receptors in the body. They can either mimic or block the effects of estrogen, depending on the tissue type. This unique ability makes SERMs useful in treating conditions like breast cancer and osteoporosis, where estrogen's role can be both beneficial and harmful. SERMs are commonly prescribed to postmenopausal women to reduce the risk of breast cancer and to improve bone density. Examples of SERMs include tamoxifen and raloxifene. By selectively targeting estrogen receptors, SERMs help manage various health issues while minimizing side effects associated with traditional hormone therapies.