Santee Bay is a coastal area located in South Carolina, near the mouth of the Santee River. It is part of the larger Santee Coastal Reserve, which includes diverse ecosystems such as marshes, wetlands, and estuaries. The bay is known for its rich biodiversity, providing habitat for various species of fish, birds, and other wildlife. The bay is also a popular spot for recreational activities like fishing, boating, and birdwatching. Its proximity to the Santee National Wildlife Refuge makes it an attractive destination for nature enthusiasts. The area's scenic beauty and ecological significance contribute to its appeal for both locals and visitors.