The Sanguinesti region is a fictional area in the game Old School RuneScape. It is known for its dark and eerie atmosphere, featuring a variety of unique monsters and quests. The region is primarily inhabited by vampires, which adds to its sinister reputation. Players often visit this area to engage in combat and complete tasks related to the Sanguinesti storyline. One of the key locations within the Sanguinesti region is Darkmeyer, the capital of the vampiric society. This city is home to various shops and services, catering to players seeking to enhance their skills and gear. The region also includes the Sanguinesti staff, a powerful weapon that players can obtain through quests.