Sanguinesti Vampires are a type of creature found in the game Old School RuneScape. They are known for their blood-sucking abilities and are often encountered in the Sanguinesti region. These vampires are characterized by their high combat level and unique attacks, making them a challenging foe for players. Players can defeat Sanguinesti Vampires to obtain valuable loot, including the Sanguinesti staff, a powerful weapon. They also drop blood shards, which can be used to create various items. Engaging with these vampires requires strategy and preparation due to their strength and special abilities.