Sandhoff Disease is a rare genetic disorder that affects the nervous system. It is caused by a deficiency of specific enzymes needed to break down certain fats in the body. This leads to the accumulation of harmful substances in the brain and other tissues, resulting in progressive neurological damage. Symptoms of Sandhoff Disease typically appear in infancy and may include muscle weakness, loss of motor skills, and vision problems. As the disease progresses, affected individuals may experience seizures and cognitive decline. There is currently no cure, and treatment focuses on managing symptoms and providing supportive care.