San Sebastiano, or Saint Sebastian, is a popular subject in art, often depicted as a young man tied to a tree or post, pierced with arrows. This imagery symbolizes his martyrdom for his Christian faith during the Roman Empire. Artists have portrayed him in various styles, from the early Christian period to the Renaissance, highlighting themes of suffering and divine protection. Notable works featuring San Sebastiano include paintings by Andrea Mantegna and Francesco Hayez, which emphasize his physical beauty and spiritual strength. His representation has inspired countless sculptures and frescoes, making him a significant figure in Christian art throughout history.