SMA Type 4
SMA Type 4, or Spinal Muscular Atrophy Type 4, is a genetic disorder that primarily affects adults. It is characterized by muscle weakness and atrophy due to the degeneration of motor neurons in the spinal cord. Symptoms typically appear in late adolescence or early adulthood, and individuals may experience difficulty with activities such as walking or climbing stairs.
Unlike other types of SMA, individuals with SMA Type 4 usually have a milder progression of symptoms and may retain some muscle strength. The condition is caused by mutations in the SMN1 gene, which is essential for the survival of motor neurons. Treatment options focus on managing symptoms and improving quality of life.