SLC26 Family
The SLC26 family consists of a group of genes that encode for membrane transport proteins. These proteins are primarily involved in the transport of anions, such as chloride and bicarbonate, across cell membranes. They play crucial roles in various physiological processes, including ion balance, pH regulation, and fluid secretion in different tissues.
Members of the SLC26 family are found in many organisms and are essential for functions in organs like the kidneys, lungs, and gastrointestinal tract. Mutations in these genes can lead to various disorders, including Pendred syndrome and Bartter syndrome, highlighting their importance in human health.