SLC22A3 is a gene that encodes a protein known as a solute carrier, which is involved in the transport of various organic compounds across cell membranes. This protein plays a crucial role in the uptake and elimination of substances, including drugs and metabolites, in different tissues of the body. The SLC22A3 protein is particularly important in the kidneys, where it helps regulate the excretion of certain compounds. Variations in this gene can influence how individuals respond to medications and may be linked to certain health conditions, highlighting its significance in pharmacogenomics and personalized medicine.