SGLTs, or Sodium-Glucose Transporters, are proteins found in the cells of the kidneys and intestines. They play a crucial role in the reabsorption of glucose from urine back into the bloodstream, helping to maintain blood sugar levels. There are different types of SGLTs, with SGLT1 and SGLT2 being the most studied. SGLT2 inhibitors are a class of medications used to treat type 2 diabetes. By blocking SGLT2, these drugs prevent glucose reabsorption, leading to increased glucose excretion in urine. This helps lower blood sugar levels and can also provide benefits for heart and kidney health.