"S-Town" is a podcast created by Brian Reed and produced by Serial Productions and This American Life. It begins with a man named John B. McLemore from Woodstock, Alabama, who invites Reed to investigate a murder in his town. However, the story evolves into a deep exploration of McLemore's life, his struggles, and the complexities of his personality. The podcast delves into themes of mental health, friendship, and the search for meaning. It combines elements of true crime with personal narrative, ultimately revealing the intricacies of small-town life and the impact of one individual's story on those around him.