S-Adenosyl Methionine, often abbreviated as SAMe, is a naturally occurring compound found in the body. It is formed from the amino acid methionine and ATP (adenosine triphosphate). SAMe plays a crucial role in various biochemical processes, including the synthesis of neurotransmitters and the regulation of mood. In addition to its role in mental health, SAMe is involved in the methylation process, which is essential for DNA regulation and the metabolism of certain compounds. It is also studied for its potential benefits in treating conditions like arthritis and liver disease, although more research is needed to confirm these effects.