Aggretsuko features a cast of characters who are friends of Retsuko, the main character. These friends include Fenneko, a clever and observant fennec fox, and Haida, a kind-hearted wolf who has a crush on Retsuko. Each character brings their unique personality and perspective to the group, providing support and humor throughout the series. Another notable friend is Gori, a strong and confident gorilla who often acts as a mentor to Retsuko. Washimi, a graceful owl, is also part of the group, known for her intelligence and professionalism. Together, they navigate the challenges of work and personal life, showcasing the importance of friendship.