Rauwolfia is a genus of flowering plants in the family Apocynaceae, primarily found in tropical regions. The most well-known species, Rauwolfia serpentina, has been traditionally used in herbal medicine for its calming effects and potential to lower blood pressure. The active compounds in Rauwolfia, particularly reserpine, have been studied for their ability to treat hypertension and certain mental health conditions. However, due to potential side effects, its use has declined in favor of modern pharmaceuticals. Rauwolfia remains significant in ethnobotany and traditional medicine practices.