RNase H
RNase H is an enzyme that plays a crucial role in the degradation of RNA molecules. It specifically recognizes and cleaves the RNA strand of RNA-DNA hybrids, which are formed during processes like DNA replication and transcription. By removing RNA from these hybrids, RNase H helps maintain the integrity of the genetic material.
This enzyme is essential for various cellular functions, including the processing of Okazaki fragments during DNA replication and the removal of RNA primers. Additionally, RNase H is important in the study of molecular biology and has applications in developing therapeutic strategies, such as antisense oligonucleotides.