The Protein Data Bank (PDB) is a comprehensive online repository that stores three-dimensional structures of biological macromolecules, primarily proteins and nucleic acids. Researchers can access detailed information about these structures, which are determined through techniques like X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy. The PDB plays a crucial role in advancing our understanding of molecular biology and drug design. Established in 1971, the PDB is maintained by the Research Collaboratory for Structural Bioinformatics (RCSB). It provides valuable resources for scientists, including visualization tools and data analysis software. By sharing structural data, the PDB fosters collaboration and innovation in fields such as biochemistry, pharmacology, and bioinformatics.