Protein aggregates are clusters of misfolded proteins that can accumulate in cells. These aggregates can disrupt normal cellular functions and are often associated with various diseases, including neurodegenerative disorders like Alzheimer's and Parkinson's. When proteins do not fold correctly, they can stick together, forming larger structures that the body struggles to eliminate. The formation of protein aggregates can result from several factors, including genetic mutations, environmental stress, and aging. Cells have mechanisms to manage and degrade these aggregates, but when these systems fail, it can lead to cellular damage and contribute to disease progression. Understanding protein aggregation is crucial for developing potential treatments.