The Plague of Cyprian was a pandemic that struck the Roman Empire from around 249 to 262 AD. Named after Saint Cyprian, a bishop of Carthage who described the outbreak, it is believed to have caused widespread illness and death. Symptoms included fever, diarrhea, and severe pain, leading to high mortality rates. This plague significantly impacted the Roman society and economy, contributing to a decline in population and labor shortages. The crisis also influenced the spread of Christianity, as many Christians cared for the sick, which helped to enhance the faith's reputation during a time of turmoil.