Phosphatidylinositol 4,5-bisphosphate (PIP2) is a phospholipid found in cell membranes, particularly in the inner leaflet. It plays a crucial role in cellular signaling and acts as a precursor for important signaling molecules. PIP2 is involved in various cellular processes, including the regulation of ion channels and the activation of certain proteins. When phospholipase C is activated, it cleaves PIP2 to produce inositol trisphosphate (IP3) and diacylglycerol (DAG), which further propagate signaling pathways. This process is essential for functions such as muscle contraction, neurotransmitter release, and cell growth.