Phantom Limb Syndrome is a condition where individuals who have lost a limb still feel sensations, including pain, in the area where the limb once was. This phenomenon occurs because the brain continues to receive signals from nerves that once connected to the missing limb, leading to the perception of its presence. The sensations can vary widely, ranging from tingling and itching to severe pain, known as phantom pain. Treatment options include medications, physical therapy, and mirror therapy, which can help alleviate symptoms by retraining the brain's perception of the missing limb.