The Pennsylvania-Ohio border is a straight line that separates the states of Pennsylvania and Ohio in the United States. It runs approximately 405 miles from the Lake Erie shoreline in the north to the Ohio River in the south. This border is significant for trade and transportation, connecting various cities and regions. Several major highways, including Interstate 80 and Interstate 76, cross the border, facilitating travel and commerce. The area is characterized by a mix of urban and rural landscapes, with cities like Pittsburgh in Pennsylvania and Youngstown in Ohio located near the border.