The Ohio River is a significant waterway in the United States, flowing approximately 981 miles from Pittsburgh, Pennsylvania to the Mississippi River. It serves as a natural border between several states, including Ohio, West Virginia, and Kentucky, and is vital for transportation and commerce in the region. Historically, the Ohio River played a crucial role in the westward expansion of the United States, serving as a key route for settlers and traders. Today, it supports various recreational activities, including fishing, boating, and hiking along its scenic banks.