Pennsylvania Route 422 is a major highway in the state of Pennsylvania, stretching approximately 70 miles. It connects the cities of Reading and Pittsburgh, serving as a vital transportation route for both local and regional traffic. The highway runs through several counties, including Berks, Chester, and Armstrong. Originally established in the early 20th century, Route 422 has undergone various upgrades and expansions to accommodate increasing traffic. It features both rural and urban landscapes, providing access to numerous communities, businesses, and recreational areas along its path.